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Am I still lactose tolerant? - Lactose Gene Therapy Update

Am I still lactose tolerant? - Lactose Gene Therapy Update on HackerTube: recommended by 3 Hacker News commenters across 3 separate months, 2020–2026.

The Thought Emporium's update on the home-brewed gene therapy he took to cure his lactose intolerance. It reports how the effect held up over two years and what future versions might look like.

Why Hacker News recommends it

Pointed to as a striking example of DIY biology and self-experimentation with gene therapy.

people recommended it
3
separate months
3
strong recommendations
1
discussed on HN
2020–2026
“His YouTube channel The Thought Emporium, is amazing.”
— stuntkite, Jun 2021, in “CRISPR gene-editing breakthrough opens door to treating broad array of diseases”

What HN commenters said

10 Hacker News comments link this video. Each one links back to its thread.

stuntkiteJun 2021Strongly recommends

His YouTube channel The Thought Emporium, is amazing. He just moved into a new lab and I really appreciate what he’s working on and how he communicates it. The robot painting fluorescent proteins is neat and recently he dropped a video demonstrating his adventures making synthetic opal. Apparently the edit made him totally lactose tolerant for over a year and now he has very mild lactose intolerance. He says he hasn’t redosed because he wants to improve the plasmid (I think that’s the right term, BUGFIX probably isn’t right) before he takes another run at it. Here’s his update video from last year on that endeavor. ▶ this video

in “CRISPR gene-editing breakthrough opens door to treating broad array of diseases” · View on HN

jcimsDec 2020Recommends

With a germ you can kill a few million people - [link] [link] [link] [link] If you want to see someone do cool stuff with the above: ▶ this video [link]

in “Girlfriend warned Nashville police Anthony Warner was building bomb a year ago” · View on HN

freezing_coffeeJul 2020Recommends

Have been a patron for some time, and discovered his channel with his lactose gene therapy video - to which he recently posted an update: ▶ this video . Great addition to scientific youtube.

in “The Thought Emporium” · View on HN

haxiomicAug 2026Cites it

There’s YouTubers who do this [0]. I’d argue estimate the risks of a synthetically induced pandemic of massive impact this century are very high - [0] ▶ this video

in “AI Can Now Design Functional Viruses. Should We Worry?” · View on HN

dlcarrierDec 2025Cites it

There was a guy on YouTube who genetically engineered himself to gain lactose tolerance. ( [link] ) It lasted for around a year and a half ( ▶ this video ) before the effect mostly wore off. He took it orally, so it only affected his intestinal lining, and I presume it didn't effect enough stem cells to get a permanent effect, but it would still be usable as something taken annually, which is still far less often than any medication.

in “Scientists Edited Genes Inside a Living Person for First Time, Saved His Life” · View on HN

ben_wJul 2024Cites it

In general, if you want to bio-hack your own body, you're allowed, nobody will stop you. e.g. ▶ this video (even going past the first treatment he did on himself, to the updated version that's not yet human-rated, it's the creator going "please don't" rather than anything enforced). The health and safety concerns about stuff like this are mostly about other people getting hurt.

in “One-dose nasal spray clears toxic Alzheimer's proteins to improve memory” · View on HN

Show 4 more comments
juliusJun 2024Cites it

Reminds me of the Youtube Guy who homebrewed a gene-therapy to treat his Lactose Intolerance, successfully ▶ this video

in “Major cause of inflammatory bowel disease discovered” · View on HN

haxiomicMar 2023Cites it

Here’s someone who orders parts from the internet to design a custom virus that genetically modifies his own cells to cure his lactose intolerance ▶ this video Pretty cool for sure and a great use of the technology. The reason more of us don’t do this is because we lack the knowledge of biology to understand what we’re doing That will soon change.

in “” · View on HN

haxiomicJul 2020Cites it

We have this today to an extent, here’s someone who tested a DIY gene editing cure for lactose intolerance on themselves ▶ this video (Spoiler: it worked, very well in fact!)

in “Scientists make precise edits to mitochondrial DNA for first time” · View on HN

h_spacerDec 2020Joke

▶ this video "I hope that this home brewed gene therapy doesn't kill me." are not words I expected to see in the first 30 seconds of a video.

in “Longbets: A bioerror will lead to one million casualties by Dec 2020” · View on HN

Topics & tags

Biology & biotechnologyMedicine & infectious diseasegene therapylactose intolerancebiohackingself-experimentthought emporium