Prof. Robert Lustig - 'Sugar, metabolic syndrome, and cancer'

Bullshit, and my response is a bit tangential, sorry. Obesity isn't a defect of self-control, it's a systematic metabolic disease that makes these people ravenous yet ingest enormous amount of calories. Low carb eating has been successful outside of the mainstream lie of "eat more whole grains" because it simply avoids the foods that worsen runaway metabolic syndrome; the common advice is just to "eat less", while these poor people are ravenous and gain fat on whole foods 2,000 kcal diets. CICO doesn't mean anything in a vacuum if one way of eating causes you to be constantly hungry, and the other teaches your body to make use of its great amount of stored energy. Obesity is eating the same food that previously kept you healthy, but now makes you sick and hungry. Here's abundance of doctors and researchers talking about it: [link] Here's one I've watched and can recommend: Prof. Robert Lustig - 'Sugar, metabolic syndrome, and cancer': ▶ this video

in “Rare genital defects seen in sons of men taking major diabetes drug” · View on HN

TIL librubberband! So, like $ mpv --af=rubberband --speed=2 --demuxer-readahead-secs=60 ▶ this video Food labeling requirements have to be counted as a success, as far as they go. And, I find it hard to criticize the execution of the tobacco advertising ban. Stringing people up has been seen to work, but most often the wrong ones get strung up.

in “Investigators say they've finally identified the Zodiac Killer” · View on HN

> Due to the laws of thermodynamics, people don't gain or lose weight "regardless of diet". Some medical conditions can reduce metabolic rate or increase hunger, but even so for every person there is a calorie intake threshold below which they will lose weight. No, AIUI there are metabolic syndromes where instead of losing weight, they'll just get sicker and die, even while gaining weight. My understanding, based on stuff I've read and talks by the likes of UCSF's Lustig on youtube, is that in some cases people can be effectively starving themselves to death internally while gaining weight eating a normal diet because most the energy consumed is being stored in fat. When you lower the caloric intake, they don't lose weight, they just keep getting sicker and can eventually die without the appropriate hormonal medication. If memory serves, one extreme example of this was a young girl with a small brain tumor whom after having it removed started putting on weight with nothing changed in her diet or lifestyle, no matter what they changed she wouldn't stop getting fatter - she just got weaker/sicker if they removed calories, while still getting fatter. They determined a region of her brain was damaged in the operation, IIRC it was the pituitary gland, and started medicating her with the necessary hormones to take its place and everything was back to normal. I'm pretty sure it was covered in one of the Lustig talks on youtube. These are really fascinating failure modes that illustr

in “Fatness and Thinness in the Middle Ages” · View on HN