Prof. Thomas Seyfried - 'Cancer as a Metabolic Disease: Implications for Novel Therapies'

My understanding is that cancer cells short circuit the krebs cycle [1] and survive off fermented fuels like glucose and most of the amino acids, l-glutamine being the most prevalent and available. Most of the population have an over-abundance of glucose. [1] - ▶ this video [video][unpopular opinion]

in “Arginine – The Nutrient That Cancer Cells Crave” · View on HN

I am not an expert in this area but I believe it may be related to the primitive mechanism the cells are capable of activating and reverting to when the mitochondria are damaged. [1] [1] - ▶ this video [video]

in “Ancient Genes for Symbiosis Hint at Mitochondria’s Origins” · View on HN

Speaking of reproducible science, I am really curious what cancer experts take is on this video [1] and their thoughts on cancer not being a somatic genetic disorder but rather that being a downstream effect of a mitochondrial metabolic disorder. [1] - ▶ this video

in “More than half of high-impact cancer lab studies could not be replicated” · View on HN

Another possibility could be what people consume and how much of it, if we start to accept that cancer may be a metabolic disease. [1] [1] - ▶ this video [video]

in “Share of Population with Cancer by Country” · View on HN

“ meaning we’ve been wrong about some basic ways in which the brain and immune system are connected.” I’ve been screaming this at my doctors for years. For those who don’t want to read the article, the quote sums it up. They discovered new lymphatic vessels in the brain in 2016 where previously the brain wasn’t thought to have any. 2 years ago I had a stressful life event. I became schizophrenic because of it. I accidentally discovered that ketosis cures the schizophrenia. It turns out a doctor at Harvard has been sounding the alarm about this and nobody is listening to him [1]. After researching these things somewhat deeply, it appears that almost all diseases that involve the death or inactivity of neurons (Alzheimer’s, schizophrenia, autism, etc) are sometimes caused by “inflammatory signals,” as I call them, which interfere with the metabolism of glucose. Note the way I worded that — there’s more than one way for those neurons to become deactivated. What we currently think of as being a single disease might be many diseases, many different types of pathology that ultimately lead to the silencing of the same general population of neurons and thereby causing the same symptoms. The point is that the metabolic angle doesn’t explain all neural pathology, so keep that in mind when ketosis is found to only put 20% of schizophrenics into remission in the next five years. There is currently exactly one study looking at the effect of ketosis on schizophrenia, in Finland, and it kee

in “A newly discovered body part changes our understanding of the brain (2016)” · View on HN

The idea that people are imagining this, as other commenters have put forward, is nonsense. The idea that people are just getting old and drink too much soda isn’t right either although it’s close. The reason why people report similar or overlapping symptoms is because they all have a problem with their immune systems. Overactive immune systems tend to cause a certain set of symptoms. The immune system is very complicated, very broad in its jurisdiction and very poorly understood. It is scientifically proven that certain chemicals (common food additives for example) cause no immune (allergic) response at all whatsoever, but cause an immune response to other chemicals. So the immune system is not just complex as a monolith but also has inputs that interact with one another, leading to a combinatoric level of complexity. When you also consider that immune function and mediation (as seen with some food additives, for example) is observed in emotional stress — something that is as close to being unquantifiable as anything could be — one can see that it might be the case that this is a disease that has evaded medical science until now. Chronic fatigue syndrome was observed in gulf war vets and was so common among them that it was coined “gulf war syndrome.” One researcher has hypothesized that this is due to an immune response which takes the form of cell deactivation via ATP signaling which he has named “cell danger response.” Meanwhile, it is widely appreciated that autism is no

in “As Their Numbers Grow, Covid-19 “Long Haulers” Stump Experts” · View on HN